cryptography is a package designed to expose cryptographic primitives and recipes to Python developers. From 45.0.0 to before 46.0.7, if a non-contiguous buffer was passed to APIs which accepted Python buffers (e.g. Hash.update()), this could lead to buffer overflows. This vulnerability is fixed in 46.0.7.
Exploitability
AV:NAC:LAT:NPR:NUI:NVulnerable System
VC:NVI:NVA:LSubsequent System
SC:NSI:NSA:N6.9/CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:N/VI:N/VA:L/SC:N/SI:N/SA:NMemory Safety