A client might theoretically be able to cause a mismatch between queries sent to a backend and the received responses by sending a flood of perfectly timed queries that are routed to a TCP-only or DNS over TLS backend.
Exploitability
AV:AAC:HPR:NUI:NScope
S:UImpact
C:NI:NA:L3.1/CVSS:3.1/AV:A/AC:H/PR:N/UI:N/S:U/C:N/I:N/A:L