The product or code uses machine-dependent functionality, but it does not sufficiently encapsulate or isolate this functionality from the rest of the code.
This issue makes it more difficult to port or maintain the product, which indirectly affects security by making it more difficult or time-consuming to find and/or fix vulnerabilities. It also might make it easier to introduce vulnerabilities.
Automated static analysis, commonly referred to as Static Application Security Testing (SAST), can find some instances of this weakness by analyzing source code (or binary/compiled code) without having to execute it. Typically, this is done by building a model of data flow and control flow, then searching for potentially-vulnerable patterns that connect "sources" (origins of input) with "sinks" (destinations where the data interacts with external components, a lower layer such as the OS, etc.)